...thelioma Blood Tests and Biomarkers: MESOMARK, Fibulin-3, HMGB1 & Emerging Diagnostics
...1px solid #dee2e6;" | MESOMARK assay (SMRP) — cleared in 2007 by Fujirebio Diagnostics for monitoring treatment response
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...oluble mesothelin-related peptides (SMRP)''', cleared in 2007 by Fujirebio Diagnostics for monitoring treatment response in confirmed patients — not for primary s
...order-bottom:1px solid #dee2e6;" | '''MESOMARK assay (SMRP)''' — Fujirebio Diagnostics, cleared 2007 for treatment monitoring in confirmed patients<ref name="fda_
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|title=Mesothelioma Molecular and Genetic Testing: BAP1, CDKN2A, NGS Panels & Biomarker-Guided Treatment
|description=Comprehensive guide to molecular and genetic testing for mesothelioma including BAP1 mutations, CDKN2A FISH,
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...pleural mesothelioma from healthy pleura and other pleural pathologies]. ''Molecular Oncology''. 2026 Apr. PMID: 41239415.</ref> Germline BAP1 testing is now an
The '''MESOMARK assay''' (Fujirebio Diagnostics) is the '''only FDA-approved serum biomarker''' for mesothelioma as of May
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=== Molecular Biomarkers in Pleural Fluid ===
Beyond standard cytology, pleural fluid is increasingly analyzed for molecular biomarkers that may improve diagnostic accuracy without requiring surgical
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| style="padding:10px; border-bottom:1px solid #dee2e6;" | 86% (molecular marker yield)
| style="padding:10px; border-bottom:1px solid #dee2e6;" | 77% (molecular marker yield)
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