Editing UCLA Health (section)

== What Clinical Trials Can Patients Access? ==

UCLA maintains an active clinical trials program, giving patients access to experimental therapies not yet available to the general public.<ref>[https://dandell.com/mesothelioma/ Mesothelioma], Danziger & De Llano</ref>

'''Current and Recent Trials'''

'''Logic-Gated CAR T-Cell Therapy (A2B694):'''
A multi-site trial evaluating the safety and efficacy of mesothelin-targeting logic-gated CAR T cells in participants with solid tumors. This next-generation approach aims to improve upon earlier CAR T technologies with enhanced targeting capabilities.

'''Cytoreductive Surgery with HIOC:'''
Study of cytoreductive surgery and hyperthermic intraoperative chemotherapy with pemetrexed and cisplatin for malignant pleural mesotheliomas.

'''MTG201 Plus Nivolumab:'''
Study in patients with relapsed pleural mesothelioma, combining novel targeted therapy with established immunotherapy.

'''MEDI4736 Studies:'''
Trials examining durvalumab alone or combined with tremelimumab in surgically resectable malignant pleural mesothelioma.

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| style="padding:15px; color:#155724;" | '''✓ Clinical Trial Access:''' UCLA patients have opportunities to participate in cutting-edge research that may provide access to tomorrow's standard treatments today. Ask your care team about eligibility for current trials.
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